Liver Intensive Care

The Liver Intensive Care has a particular pedigree in the management of acute and chronic liver disease. It treats more patients with acute liver failure than any other centre in the world and supports Europe’s largest liver transplantation programme.
In the ICU setting, the main focal points are hemodynamic stabilization, coagulation and electrolyte disturbances correction, respiratory support, early weaning from mechanical ventilation, and evaluation of graft functionality. It is of paramount importance to facilitate early graft recovery, recognize and promptly treat systematic complications and life-threatening sequelae, and individualize treatment protocols considering graft quality, donor’s and recipient’s health status, and potential co-morbidities. To achieve those goals, technological advancements in continuous patient monitoring, graft functionality, and its metabolic reserves must be assimilated and implemented in the ICU.

  • ALF causes multi-system failure. The most dangerous consequences of ALF are
  • Cerebral oedema and the risk of tentorial herniation, severe vasodilatory shock, lactic
  • Acidosis and hypoglycaemia. Acute renal failure will almost always follow.
  • Coagulopathy, although often profound, rarely results in catastrophic bleeding.

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